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Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia

May 17, 2024

Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…

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