Motivating Physical Activity with a Walking Exercise Behaviour Intervention and Pain Management Remotely in Intermittent Claudication (MAvERIC): protocol for a randomised controlled feasibility trial

May 16, 2024

Introduction Peripheral arterial disease (PAD) affects approximately one in five people aged >60 years.1,2 In addition, 40–75% of these people experience intermittent claudication (IC), a chronic manifestation of PAD which commonly presents as limb pain and reduced exercise tolerance.3,4 People with PAD and IC experience disability and impaired quality of life due to reduced physical…

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Surgical Site Infections in Major Lower Limb Amputation: An International Multicentre Audit (SIMBA): Study Protocol

February 29, 2024

Introduction Background and rationale Surgical site infection (SSI) is a significant potential complication of any surgical procedure, acknowledged by the National Institute of Health and Care Excellence (NICE) as a leading cause of in-hospital morbidity and mortality.1 In vascular surgery, patients undergoing major lower limb amputation (MLLA) may be at an increased risk of developing…

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The FraiLTI (Frailty in chronic Limb-Threatening Ischaemia) Protocol

February 28, 2024

Introduction Frailty, a concept gaining significant attention in recent years, is defined as a clinically recognisable state of increased vulnerability resulting from ageing-associated decline in reserve and function across multiple physiologic systems such that the ability to cope with everyday or acute stressors is compromised.1 Frailty leaves patients vulnerable to stressors such as illness, trauma…

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The clinical effectiveness of waxing or epilation compared with other methods of hair removal in reducing the incidence of surgical site infections: a protocol for a systematic review

November 20, 2023

Background Hair has traditionally been removed from surgical sites preoperatively, but there is gathering evidence that some methods of hair removal can increase the risk of surgical site infections (SSIs).1,2 The most recent Cochrane review (2021) found that, while hair removal using clippers or depilatory cream does not significantly increase the risk of SSIs, razors…

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Use of Shockwave® intravascular lithotripsy in the treatment of calcific peripheral vascular disease of the crural vessels: a protocol for a systematic review

February 26, 2023

Introduction Peripheral artery disease (PAD) is a systemic atherosclerotic disease with an increasing prevalence currently estimated at over 230 million adults globally.1,2  PAD prevalence in the infrapopliteal/ crural arterial bed is increasing, influenced by the ageing population, as well as the increasing prevalence of diabetes and chronic kidney disease.1–3 Chronic limb-threatening ischaemia (CLTI), the most…

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