Protocol
Surgical wound healing by secondary intention versus primary and delayed primary closure: systematic review protocol
Background Every year 4.4 million surgical procedures are undertaken under the National Health Service (NHS) in England.1 Incisions made during these procedures are ideally closed immediately after surgery, known as primary closure or healing by primary intent. In some circumstances the incision is left open and allowed to heal from the base upwards through granulation,…
Protocol for the Physical Activity after Cardiovascular Screening (PACS) study in women aged 60–69 years: a prospective observational cohort study
Introduction Women with cardiovascular disease receive a poorer standard of care than men; they are more likely to be misdiagnosed and undertreated.1 Contributing factors include failure to recognise the importance of secondary prevention, sex-related differences in clinical presentation, delays in seeking care and misperceptions about cardiovascular disease in women.1 These issues also contribute to elevated…
The use of non-steroidal anti-inflammatory drugs for the prevention and reduction of pain following superficial venous incompetence treatment: a systematic review protocol
Introduction Superficial venous incompetence (SVI) is among the most common chronic diseases in adults. Approximately one-third of the general population is affected, with the main risk factors being older age, parity, obesity and family history.1–3 The disease commonly manifests as varicose veins, which are tortuous and dilated superficial veins in the lower extremities. It also…
Validation of the Clinical Frailty Scale in vascular surgery: a protocol
Introduction As life expectancy increases, so does the prevalence of older patients and age-related health conditions. Frailty is one such condition which has become increasingly recognised as a clinical syndrome, distinct from chronological age, disability and comorbidity.1–3 A complex, dynamic and multifactorial syndrome, frailty may be theoretically defined as ‘a state of increased vulnerability, resulting…
