peripheral artery disease
An audit of glycaemic control and impact on surgical outcomes among inpatients with critical limb-threatening ischaemia (CLTI)
Introduction Chronic limb-threatening ischaemia (CLTI) is the most severe presentation of peripheral arterial disease (PAD) and affects 1% of the population in the UK.1 PAD is a common disease among patients with diabetes mellitus,2 and the relative risk of PAD increases with increasing duration and severity of diabetes.3 As diabetes is a major driver of…
Read MoreSingle-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia
Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…
Read MoreSingle-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia
Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…
Read MoreUse of Shockwave® intravascular lithotripsy in the treatment of calcific peripheral vascular disease of the crural vessels: a protocol for a systematic review
Introduction Peripheral artery disease (PAD) is a systemic atherosclerotic disease with an increasing prevalence currently estimated at over 230 million adults globally.1,2 PAD prevalence in the infrapopliteal/ crural arterial bed is increasing, influenced by the ageing population, as well as the increasing prevalence of diabetes and chronic kidney disease.1–3 Chronic limb-threatening ischaemia (CLTI), the most…
Read MoreCommunity WALKing and home-baSed circuiT tRaining in peOple liviNG with intermittent claudication (WALK-STRONG): protocol for a randomised controlled feasibility trial
Introduction Peripheral artery disease (PAD) refers to the progressive occlusion of the arteries supplying the lower limbs1 and affects over an estimated 236 million people worldwide.2 Sustained ischaemia to the lower limbs, resulting in an oxygen supply/demand imbalance, can lead to a symptomatic presentation of PAD, characterised by exertional cramp-like leg pain known as intermittent…
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