peripheral artery disease
Evaluation of contemporary calcium scoring methods in peripheral artery disease
Introduction Vessel calcification (VC) of the peripheral arteries poses a significant challenge to endovascular treatment of peripheral arterial disease (PAD)1 due to its association with poorer outcomes.2 The importance of VC is highlighted in it being a research priority for the assessment of PAD and chronic limb threatening ischaemia.3,4 To date, there has yet to…
An audit of glycaemic control and impact on surgical outcomes among inpatients with critical limb-threatening ischaemia (CLTI)
Introduction Chronic limb-threatening ischaemia (CLTI) is the most severe presentation of peripheral arterial disease (PAD) and affects 1% of the population in the UK.1 PAD is a common disease among patients with diabetes mellitus,2 and the relative risk of PAD increases with increasing duration and severity of diabetes.3 As diabetes is a major driver of…
Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia
Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…
Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia
Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…
Use of Shockwave® intravascular lithotripsy in the treatment of calcific peripheral vascular disease of the crural vessels: a protocol for a systematic review
Introduction Peripheral artery disease (PAD) is a systemic atherosclerotic disease with an increasing prevalence currently estimated at over 230 million adults globally.1,2 PAD prevalence in the infrapopliteal/ crural arterial bed is increasing, influenced by the ageing population, as well as the increasing prevalence of diabetes and chronic kidney disease.1–3 Chronic limb-threatening ischaemia (CLTI), the most…
