Cohort Study
Prognostic value of simple frailty and malnutrition screening tools for determining surgical risk in patients with chronic limb threatening ischaemia undergoing major vascular surgery: a retrospective cross-sectional study
Introduction Chronic limb threatening ischaemia (CLTI) is a severe manifestation of peripheral arterial disease (PAD), characterised by intractable rest pain with or without tissue loss in the form of ulceration and/or gangrene or infection.1 Approximately 1% of all PAD cases are due to CLTI and first-line treatment includes revascularisation, primary amputation or, in some cases,…
Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia
Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…
SHOCkwave lithotripsy for patients with peripheral arterial disease: the SHOCC study
Introduction Peripheral artery disease (PAD) represents a major health problem worldwide, affecting one-fifth of people over the age of 60 in the UK.1–3 It is the most common cause of lower limb amputation.4 Most patients with chronic limb threatening ischaemia (CLTI) and some patients with severe claudication will require lower limb revascularisation, one of the…
Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia
Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…
