chronic limb-threatening ischaemia

Surgical Site Infections in Major Lower Limb Amputation: An International Multicentre Audit (SIMBA): Study Protocol

February 29, 2024

Introduction Background and rationale Surgical site infection (SSI) is a significant potential complication of any surgical procedure, acknowledged by the National Institute of Health and Care Excellence (NICE) as a leading cause of in-hospital morbidity and mortality.1 In vascular surgery, patients undergoing major lower limb amputation (MLLA) may be at an increased risk of developing…

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Effect of health literacy and socioeconomic deprivation on outcomes after lower limb surgical revascularisation for chronic limb-threatening ischaemia: the HeaLTHI study

November 8, 2023

Introduction Health literacy is the degree to which individuals have the capacity to obtain, process and understand basic health information and access services needed to make appropriate health decisions.1 Health literacy is a complex concept that is influenced by an individual’s educational attainment, race, age, deprivation and available healthcare services.2,3 There are a number of…

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Outcome of covered stents for severe aorto-iliac occlusive disease (AIOD) in patients with chronic limb-threatening ischaemia

March 14, 2023

Introduction The most recent iteration of the Inter-Society Consensus Document for the Management of Peripheral Arterial Disease from 2015 (Trans-Atlantic Inter-Society Consensus; TASC II) has suggested that all types of aorto-iliac occlusive disease (AIOD) may be treated using either an endovascular or open approach, provided the clinical team has sufficient expertise in the given modality,…

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Use of Shockwave® intravascular lithotripsy in the treatment of calcific peripheral vascular disease of the crural vessels: a protocol for a systematic review

February 26, 2023

Introduction Peripheral artery disease (PAD) is a systemic atherosclerotic disease with an increasing prevalence currently estimated at over 230 million adults globally.1,2  PAD prevalence in the infrapopliteal/ crural arterial bed is increasing, influenced by the ageing population, as well as the increasing prevalence of diabetes and chronic kidney disease.1–3 Chronic limb-threatening ischaemia (CLTI), the most…

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The role of Braden scores in predicting outcomes following revascularisation for chronic limb-threatening ischaemia and their association with frailty

February 7, 2023

Introduction Peripheral artery disease (PAD) poses a substantial healthcare burden worldwide as the third leading cause of atherosclerotic vascular morbidity.1 Chronic limb-threatening ischaemia (CLTI) induces rest pain and/or tissue loss and encompasses the end stage of PAD, developing in approximately 11% of PAD patients, and is associated with debilitating pain, poor quality of life, one-year…

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