chronic limb-threatening ischaemia

Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia

May 22, 2024

Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…

Single-centre prospective cohort study investigating the associations and one-year trends of frailty, cognition, disability and quality of life pre- and post-intervention for chronic limb-threatening ischaemia

May 17, 2024

Introduction Frailty is a complex, dynamic, multi-system health state characterised by susceptibility to significant homeostatic dysregulation from even minor physiological stressors, leading to poor health-related outcomes such as loss of independence and death.1,2 Frailty is present in around half of all individuals with chronic limb-threatening ischaemia (CLTI) and is related to severity of disease.3-5 Among…

Surgical Site Infections in Major Lower Limb Amputation: An International Multicentre Audit (SIMBA): Study Protocol

February 29, 2024

Introduction Background and rationale Surgical site infection (SSI) is a significant potential complication of any surgical procedure, acknowledged by the National Institute of Health and Care Excellence (NICE) as a leading cause of in-hospital morbidity and mortality.1 In vascular surgery, patients undergoing major lower limb amputation (MLLA) may be at an increased risk of developing…

Effect of health literacy and socioeconomic deprivation on outcomes after lower limb surgical revascularisation for chronic limb-threatening ischaemia: the HeaLTHI study

November 8, 2023

Introduction Health literacy is the degree to which individuals have the capacity to obtain, process and understand basic health information and access services needed to make appropriate health decisions.1 Health literacy is a complex concept that is influenced by an individual’s educational attainment, race, age, deprivation and available healthcare services.2,3 There are a number of…

Outcome of covered stents for severe aorto-iliac occlusive disease (AIOD) in patients with chronic limb-threatening ischaemia

March 14, 2023

Introduction The most recent iteration of the Inter-Society Consensus Document for the Management of Peripheral Arterial Disease from 2015 (Trans-Atlantic Inter-Society Consensus; TASC II) has suggested that all types of aorto-iliac occlusive disease (AIOD) may be treated using either an endovascular or open approach, provided the clinical team has sufficient expertise in the given modality,…