peripheral arterial disease

Long-term outcomes of major and minor lower limb amputation: eight-year retrospective analysis from a single tertiary referral centre

February 28, 2024

Introduction Major amputation is a life-changing yet common endpoint in the management of diabetic foot disease (DFD) and chronic limb-threatening ischaemia (CLTI). Less commonly, amputation is performed for traumatic limb injury, deformity, chronic pain or loss of function.1–4 Major amputation is estimated to affect 3–4% of all patients with peripheral arterial disease (PAD)5 and 15–20%…

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Supervised exercise therapy apps for claudication

September 28, 2023

Peripheral arterial disease (PAD) has been recognised as a healthcare burden affecting up to 5.56% of the global population over 25 years of age.1 Intermittent claudication (IC) is often debilitating and results in reduced physical activity which is associated with increased cardiovascular disease and all-cause mortality.2,3 Early identification and management of PAD is essential to…

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Perception and acceptability of open versus endovascular treatment of common femoral artery disease: barriers and facilitators for randomised controlled trials

July 21, 2023

Introduction The standard of care for the treatment of atherosclerotic disease of the common femoral artery (CFA) remains open surgical CFA endarterectomy (CFAE). Endovascular interventions, however, have become first-line therapies for atherosclerotic disease of other arterial segments. This is due to their minimally invasive nature, low rates of perioperative complications and patient preference.1–4 High rates…

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Distal venous arterialisation for ‘no-option’ chronic limb-threatening ischaemia

March 29, 2022

Abstract Chronic limb-threatening ischaemia (CLTI), defined as significant peripheral arterial disease causing ischaemic rest pain and/or tissue loss, is associated with a high amputation and mortality rate. Avoiding amputation in CLTI is crucial and restoration of blood flow is usually achieved using endovascular or open surgical revascularisation. However, significant occlusion of the distal limb vasculature…

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The Vascular PAD-QIF CQUIN: what is it, why is it important, what does it mean for vascular units?

March 29, 2022

The Commissioning for Quality and Innovation (CQUIN) indicators for 2022/23 were recently published by NHS England and for the first time include a vascular indicator, the “Achievement of revascularisation standards for lower limb ischaemia”.1 This is great news and will drive quality improvement for patients with chronic limb-threatening ischaemia (CLTI). In this editorial we describe…

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