diabetes

Surgical Site Infections in Major Lower Limb Amputation – Transmetatarsal Extension (SIMBA-T): an international multicentre audit: study protocol

October 29, 2025

Introduction Background and rationale In patients with chronic limb threatening ischaemia (CLTI) or diabetes related foot complications, transmetatarsal amputation (TMA) is often required to treat serious infection or remove gangrenous digits to promote a healing wound. This is often accompanied by an attempt at revascularisation of the limb. TMA preserves limb length as well…

An audit of glycaemic control and impact on surgical outcomes among inpatients with critical limb-threatening ischaemia (CLTI)

August 27, 2025

Introduction Chronic limb-threatening ischaemia (CLTI) is the most severe presentation of peripheral arterial disease (PAD) and affects 1% of the population in the UK.1 PAD is a common disease among patients with diabetes mellitus,2 and the relative risk of PAD increases with increasing duration and severity of diabetes.3 As diabetes is a major driver of…

Surgical Site Infections in Major Lower Limb Amputation: An International Multicentre Audit (SIMBA): Study Protocol

February 29, 2024

Introduction Background and rationale Surgical site infection (SSI) is a significant potential complication of any surgical procedure, acknowledged by the National Institute of Health and Care Excellence (NICE) as a leading cause of in-hospital morbidity and mortality.1 In vascular surgery, patients undergoing major lower limb amputation (MLLA) may be at an increased risk of developing…