Long-term outcomes of major and minor lower limb amputation: eight-year retrospective analysis from a single tertiary referral centre

February 28, 2024

Introduction Major amputation is a life-changing yet common endpoint in the management of diabetic foot disease (DFD) and chronic limb-threatening ischaemia (CLTI). Less commonly, amputation is performed for traumatic limb injury, deformity, chronic pain or loss of function.1–4 Major amputation is estimated to affect 3–4% of all patients with peripheral arterial disease (PAD)5 and 15–20%…

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Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: a systematic review

November 20, 2023

Introduction Patients with abdominal aortic aneurysms (AAA) are usually older adults with widespread atherosclerosis and considerable cardiovascular risk factors.1–3 As a result, open surgical repair is associated with significant perioperative morbidity which may require a prolonged inpatient or intensive care stay.4,5  The associated metabolic and cardiopulmonary challenges may have substantial resultant consequences on functional status…

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Exploring the assessment, diagnosis and conservative management of patients with neurogenic thoracic outlet syndrome (NTOS): an online survey of UK medical and allied health professionals

November 19, 2023

Introduction Thoracic outlet syndrome (TOS) is a highly controversial medical diagnosis, as highlighted in a Cochrane review by Povlsen et al in 2014.1 Diagnosis is challenging due to the existence of four reported subgroups of TOS – namely, neurogenic, arterial, vascular and disputed – each presenting with diverse and wide-ranging symptoms.1-3 Authors describe three pertinent…

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Surgical and rehabilitation outcomes of patients undergoing through knee amputation compared with above knee amputation

July 5, 2023

Introduction Every year more than 5,000 patients undergo a major lower limb amputation in the UK.1-3 Major lower limb amputation is a pivotal life-changing event which can result in significant physical and psychological impacts, depending on the person’s functional ability pre-amputation, the cause of their amputation, their co-morbidities and the level of amputation.4,5 Below knee…

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Changes in functional health status following open abdominal aortic aneurysm repair and the role of exercise-based rehabilitation: protocol for a systematic review and meta-analysis

November 21, 2022

Introduction Abdominal aortic aneurysm (AAA) repair may be associated with significant perioperative respiratory, cardiac, distal arterial or renal complications, which might necessitate a prolonged intensive care or hospital stay.1–3 In addition, patients with AAA are frequently elderly with widespread atherosclerosis, cardiovascular risk factors and comorbidities.4-8 This, in combination with the fact that AAA repair is…

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